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Fresh vs. Frozen Embryo Transfers: Which Is Better?

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Periodically I am asked my opinion on fresh vs. frozen embryo transfer. I’m not really the professional to answer that question. Your question should be directed to your physician. They can best explain their cryopreservation methods and success rates for their practice.

This article by Dr. Michael A. Feinman, MD, FACOG may be of some value:


 

It is interesting and even amusing to see how certain concepts come full-circle and even flip-flop, over time. The debate over fresh vs. frozen transfers is one of these.

For the first 20 years of IVF history, it was a general given that fresh embryo transfers were superior to frozen ones.  Early attempts at freezing all the embryos and subsequently transferring them did not go well.  Two theories are used to support this approach.  The first is that freezing embryos would somehow sort out the better ones, as the less viable embryos would like not survive the thaw.  A sort of embryo “stress test.”  The second is that the uterine environment during a stimulated cycle is less conducive to implantation, so delaying the transfer may improve implantation. Continue reading…


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